Ribacer

Rebamipide 100mg Tablets

Ribacer Tablets

Uses and Benefits

Ribacer (Rebamipide 100mg) is prescribed for the management and prevention of gastric ulcers, gastritis, and stomach mucosal injuries. Key benefits include:

  • Promotes gastric mucosal repair and regeneration.
  • Reduces inflammation and oxidative stress in the gastrointestinal tract.
  • Enhances mucus secretion, strengthening the stomach’s protective barrier.
  • Prevents ulcer recurrence caused by NSAIDs (e.g., aspirin, ibuprofen) or H. pylori infections.

Ideal for patients with chronic gastritis, peptic ulcers, or those at risk of NSAID-induced gastric damage.

Mechanism of Action

Rebamipide works by:

  • Stimulating prostaglandin synthesis to enhance mucosal blood flow and repair.
  • Activating growth factors (e.g., epidermal growth factor) to accelerate tissue healing.
  • Scavenging free radicals, reducing oxidative damage to gastric cells.
  • Increasing mucus production and bicarbonate secretion, protecting the stomach lining.
Contraindications & Cautions

Consult your doctor before use if you:

  • Have hypersensitivity to Rebamipide or any ingredient.
  • Are pregnant or breastfeeding (limited safety data).
  • Have severe renal or hepatic impairment.
Avoid with:
  • Alcohol (increases gastric irritation).
  • NSAIDs (monitor for ulcer risk despite protective effects).
Side Effects

Common side effects (when taken as directed):

  • Mild gastrointestinal discomfort (bloating, constipation, diarrhea).
  • Dizziness or headache.
  • Skin rash or itching.

Severe reactions (seek immediate help):

  • Severe abdominal pain, blood in stool/vomit, swelling of face/tongue.
How to Use
  • Dosage: Take 1 tablet thrice daily (morning, afternoon, night) before meals.
  • Swallow whole with water; do not crush or chew.
  • Missed Dose: Take as soon as remembered. Skip if close to the next dose. Do not double dose.
  • Storage: Keep at 15–30°C in a dry place. Protect from light.
Warnings
  • Pregnancy: Category N (Not classified). Avoid unless benefits outweigh risks.
  • Renal Impairment: Use with caution; dosage adjustment may be needed.
  • Chronic Use: Long-term therapy requires periodic monitoring of gastric health.
Drug Interactions
  • NSAIDs (Ibuprofen, Aspirin): Ribacer reduces ulcer risk but does not eliminate it.
  • Anticoagulants (Warfarin): No direct interaction, but monitor for gastric bleeding.
  • Antacids: Separate administration by 2 hours to avoid reduced Rebamipide absorption.

Composition

Each film-coated tablet contains:

  • Active Ingredient: Rebamipide 100 MG
  • Inactive Ingredients: Microcrystalline cellulose, magnesium stearate, hypromellose (as per formulation).

Q1. How long should I take Ribacer?
Duration depends on the condition. Acute gastritis may require 2–4 weeks; chronic ulcers may need 8–12 weeks. Follow your doctor’s advice.

Q2. Can Ribacer be taken with alcohol?
No. Alcohol irritates the stomach lining and counteracts the medication’s protective effects.

Q3. Is Ribacer safe for elderly patients?
Yes, but reduce dosage if renal function is impaired.

Q4. Does it cause drowsiness?
Rarely. If dizziness occurs, avoid driving or operating machinery.

Q5. Can it treat H. pylori infections?
No. Ribacer is adjunctive therapy; combine with antibiotics for H. pylori eradication.